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Thermogenesis increases noticeably, with some researchers reporting feeling warmer than usual, increased sweating during physical activity, and elevated resting metabolic rate

Additionally, mercury orange staining and FACS analysis revealed that Sag caused a depletion of intracellular glutathione (GSH) specifically in Daudi, Raji, and Jurkat cells, but not in Hut-78 or normal BT cells

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The exact mechanism of these changes is still being investigated