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Each mL of sterile aqueous solution contains: COMPONENTS Cyanocobalamin (Vitamin B12) 5000 mcg, Benzyl Alcohol (preservative) 1.0% v/v, Sodium Chloride 0.22% w/v, Ammonium Sulfate 0.1% w/v, Citric Acid 0.01% w/v, Sodium Citrate 0.008% w/v

As expected, administration of BSO in the established high ACTL6A-expressing PDX tumors (cases 1 and 3) attenuated tumor progression

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These cation-selective ligand-gated ion channels are activated by the excitatory neurotransmitter glutamate and mediate fast excitatory synaptic transmission in mammalian brains 1,2

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