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2016 Nov 28;5:183
Dietary compounds such as flavonoids and isothiocyanates can stimulate the Nrf2 pathway, leading to the expression of various antioxidant enzymes and detoxifying proteins 12,13,14
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When the intestinal barrier is compromised, increased antigen exposure activates these mast cells, creating a systemic inflammatory state that amplifies allergic reactivity everywhere
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