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By targeting both receptors, Tirzepatide enhances insulin secretion and reduces glucagon secretion in a glucose-dependent manner, contributing to improved glycemic control
However, as proposed in the new CBT for BED approach, these medications may be suitable for patients with BED associated with clinical obesity without an overvaluation of shape and weight, without a history of anorexia nervosa or bulimia nervosa, and other severe, unstable mental disorders, who have successfully adopted a regular eating pattern and significantly reduced binge-eating episodes
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Gastroenterology 132:213157
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