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Common adverse effects include gastrointestinal symptoms (nausea, vomiting, diarrhea), which can lead to dehydration and electrolyte imbalances
Reagents GLP-1(736), GLP-1(936), exendin-4 and exendin(939) were from Bachem (Weil am Rhein, Germany), the glucagon receptor (GCGR) antagonist REMD2.59 was from REMD Bioptherapeutics (Camarillo, CA, USA) and pertussis toxin (PTX) was from Sigma (Gillingham, Dorset, UK)
For weight management specifically, semaglutide (Wegovy, also approved for adolescents 12 years), liraglutide 3 mg (Saxenda), and tirzepatide (Zepbound) have received FDA approval
(e) case reports and case series, ongoing and unpublished studies
A practical fertility-focused dose for you to aim at is 12 g of EPA + DHA daily, in line with the trial protocols pooled in the meta-analysis above
