Long-Term Tolerability: We need to know if the side effects remain manageable over years of continuous use
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Again, the downsides of poorly controlled glucose and weight regain make this a poor approach to management since both hyperglycemia and increasing body mass index are associated with worse perioperative outcomes
doi: 10.1111/dom.v22.11 59 MeekerRBWilliamsKKillebrewDAHudsonLC
After prolonged exposure, more extreme symptoms become noticeable, including hallucination, incoordinate movements, paralysis, convulsion, loss of consciousness and ataxia (Flora et al ., 2006)