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however, the trim-and-fill method indicated that this publication bias did not change the statistical significance of the estimate

Seek medical advice for persistent heartburn, difficulty swallowing, unintentional weight loss, or signs of gastrointestinal bleeding

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Tirzepatide gives people a window of reduced appetite during which they can establish healthier eating patterns, develop exercise habits, and restructure their relationship with food

[21] [3] If you find these symptoms particularly troublesome, your healthcare provider can discuss management strategies or alternative treatment options