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Spinal microglial beta-endorphin signaling mediates IL-10 and exenatide-induced inhibition of synaptic plasticity in neuropathic pain

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Presented for research literature review only Launay JM et al

Initiation of a GLP-1 receptor agonist was associated with reduced risk of composite endpoint of all SUDs (hazard ratio 0.86 (0.83 to 0.88), NRD 6.61 (7.95 to 5.26)) (fig 3, fig 4 and supplementary table S6)

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