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Cytochrome c also binds to cardiolipin, and the Cytochrome c-cardiolipin conjugate opens up lipid pores in the membrane, resulting in the release of cytochrome c into the cytoplasm, thus facilitating its own escape and initiating an apoptosis cascade ( Table 1 provides a list of proteins that can form oligomers and interact with cardiolipin to induce pore formation and disease processes, with associated references

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L.OkayamaH.ShiraishiK.KuaL

Type of study: non-rct in vitro Number of citations: 25 Year: 2000 Authors: J

This constellation of pathology is collectively termed diabetic panvascular disease (DPD), reflecting common molecular mechanisms and interdependent risks among vascular complications