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This, in turn, may treat ED ( For example, a small 2011 study in 24 men with mild ED and conditions associated with ED, like high blood pressure and diabetes, found that taking 1.5 g of L-citrulline daily significantly improved symptoms in 50% of participants after 1 month ( In another 30-day study in men, taking a daily combination of 800 mg of L-citrulline and 300 mg of trans-resveratrol combined with a prescription ED medication improved erectile function and hardness, compared with the placebo treatment ( Trans-resveratrol, commonly known as resveratrol, is a plant compound that functions as an antioxidant and is linked to numerous health benefits ( L-citrulline is available as a dietary supplement in capsule or powder form but is naturally present in foods like watermelon, dark chocolate, and nuts