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Compounded semaglutide is a customized version of the GLP-1 receptor agonist created by licensed 503A compounding pharmacies rather than manufactured by major pharmaceutical companies
Clinical observations describing reduced protein intake, variability in lean mass trajectories, and micronutrient insufficiency during pharmacologically induced weight loss [40, 75, 94, 95] suggest that long-term metabolic stability may become sensitive to substrate availability even in the absence of overt deficiency
Compounded drugs can be important for overcoming shortages or meeting unique patient needs but compounders should not try to compound drugs in a way that circumvents FDAs approval process, Makary said
Adam Piore can be reached at [email protected].
