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Vitamin B12 injections are an effective way to treat a deficiency, but they're not for everyone
While subcutaneous injection is the most common method of administration for peptides, some peptides may be more effective when injected directly into a muscle [3]
The extent to which a once-weekly, continuously present amylin analogue reproduces these meal-linked effects as opposed to producing a tonic, non-pulsatile signal quite unlike physiological amylin is a genuinely open question, discussed further in our review of how cagrilintide affects gastric emptying and postprandial metabolism
Heterogeneity of release probability, facilitation, and depletion at central synapses
Its use is limited to research settings due to the lack of FDA approval
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