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Threonine 188 is critical for interaction with NAD+ in research subjects [PMID: 10198228] Laboratory literature summary: Threonine 188 is critical for interaction with NAD+ in research subjects NAD+-dependent 15-hydroxyprostaglandin dehydrogenase
The liver serves as a storage site for this vitamin
Higher daily-loading models (100-200 mg daily for 7-10 days) appear in clinic protocols and are typically reserved for supervised settings
So rather than indulge in a splash of spirits, your better option is a nonalcoholic hot toddy (lemon tea with honey and, perhaps, a bit of fresh ginger for spice)
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