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The ADA/EASD consensus on glycaemic management algorithm already includes GLP-1 receptor agonists with cardiovascular benefit as an option for people with CKD when SGLT2 inhibitors are contraindicated or not tolerated, in order to reduce the risk of cardiovascular disease (Davies et al, 2022)
The endpoints aren't dramatic
While doctors and patient advocates say these drugs are critical to helping patients struggling with obesity and can save money in the long run by reducing comorbidities such as heart disease, others say the medications are just too expensive for most states to afford
Many injection pens are single-use and pre-measured, which may reduce the risk of error
But oral medication does not remove the need for medical supervision
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