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Strikingly, the study revealed that the immune cells of these patients act as an "energy sink." In a desperate attempt to survive the overwhelming oxidative stress, the immune cells upregulate their own intracellular glutathione production

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Results Later Period Baseline Demographic and Clinical Characteristics SGLT2i Cohort After applying all inclusion and exclusion criteria, the new-user cohort included 94,080 patients with a mean age of 73.1 (SD 8.9) years, of whom 47.0% were female, 56.1% were white, 46.0% had obesity, and 26.0% were current smokers (Table 1)