Mounjaro mimics both the GLP-1 and GIP hormones, but it's not a hormone itself
It also slows down the speed at which your stomach empties, a process called gastric emptying
[24] Finally, a 2020 Cochrane systematic review found insufficient evidence to suggest that metformin monotherapy reduced all-cause mortality, serious adverse events, cardiovascular mortality, non-fatal myocardial infarction, non-fatal stroke, or end-stage renal disease when compared to DPP-4 inhibitors for the treatment of type 2 diabetes
The compound is still investigational, studied under the TRIUMPH Phase 3 program ( NCT04881760 )
For prophylaxis of migraine headaches, valproate is contraindicated in women who are pregnant and in women of childbearing potential who are not using effective contraception [seeContraindications (4)]