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Doctors and patients need to know the right dose
In addition to AD, alterations in intracellular zinc homeostasis are considered a critical factor in the development of PD
They can reduce levels of Bcl-2 and increase levels of Bax and caspase-3, two proteins that promote cell death, and trigger mitochondrial mediated apoptosis
Indeed, drug resistance is also related to increase discharge (efflux) of anticancer drugs due to the overexpression of the efflux transporters
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