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We previously found that fusion of a peptide or a single-chain variable fragment to the C-terminal end of albumin reduced FcRn binding up to 2-fold, and to a greater extent than when fused to the N-terminal end 12
pylori ( 38)
A simpler surrogate is the acetaminophen (paracetamol) absorption test : because acetaminophen is negligibly absorbed by the stomach but rapidly absorbed by the small intestine, the rise in its plasma concentration tracks the rate of gastric emptying a convenient method often embedded in early-phase metabolic studies
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However, in the non-senescent control fibroblast model cultured in 10% FBS DMEM treated with or without FOXO4-DRI (25 M), no SA--gal-positive cells were observed both in keloid fibroblasts and in normal skin fibroblasts (Supplementary Fig
