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Notes Many osteoarthritis trials struggle to achieve between-group differences of even 8 points
GLP-1 is a gut hormone that the body naturally releases after eating to help reduce blood sugar levels
It is a once-weekly injection that is unique because its the first combination of two classes of medications: a glucagon-like peptide-1 (GLP-1) receptor agonist and a glucose-dependent insulinotropic polypeptide (GIP) receptor agonist
doi: 10.1016/j.jdiacomp.2015.12.027 3 VigneriPFrascaFSciaccaLPandiniGVigneriR
Its profile has supported research into coordinated endocrine signaling, metabolic adaptation, weight-related biology, glucose regulation, and energy expenditure
