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Topical trials measured skin endpoints at 8-12 weeks

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Individuals with GHD do not produce sufficient amounts of GH, which leads to growth failure in children and metabolic issues in adults

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CBS first catalyzes the -substitution reaction of L-homocysteine (L-Hcy) with L-serine to produce cystathionine, followed by , -elimination reactions of CSE, which catalyzes the production of cystathiones to produce L-cysteine (L-Cys), -ketobutyric acid, and NH 3

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