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Curr Drug Targets 5:565571 Perry T, Haughey NJ, Mattson MP, Egan JM, Greig NH (2002) Protection and reversal of excitotoxic neuronal damage by glucagon-like peptide-1 and exendin-4
In 2024 the Food and Drug Administration added cardiovascular risk as a reason to be prescribed the GLP-1 drug Wegovy, grounded in results from a major trial that showed fewer heart attacks, strokes, and cardiovascular deaths in adults with obesity or overweight and established heart disease
Among American adults who have taken these medications, 62% said they used them both to treat a chronic condition such as diabetes or heart disease and to lose weight, including 39% who said they used the medications only to treat a chronic condition
Now available in injectable (Wegovy) and oral (Wegovy pill) formulations, it remains the most widely prescribed incretin for weight management
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