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Safety Profile and Side Effects Retatrutides side effect profile in Phase 2 trials was broadly consistent with other GLP-1 class therapies primarily gastrointestinal, primarily dose-dependent, and primarily manageable
It's commonly dosed as a small nightly subcutaneous injection before bed often on a 5-days-on, 2-days-off schedule because GH is naturally released during sleep
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And, in fact, this is exactly what happens in the intestines
The most interesting thing about the study is perhaps not only the results themselves, but what they potentially tell us about the GLP-1 system and the brain
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