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Some reactions users have reported include: Mild skin rash or irritation Stomach upset and possible nausea Temporary increases in liver enzymes Fatigue or headache For those rare folks with glutathione hypersensitivity (an allergy, basically), the reaction can be more intense

A ratio of 8:1 to 15:1 zinc to copper generally maintains balance

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Split dosing becomes valuable when single dosing produces inconsistent results, when doses above 400mcg are needed, or when evening administration fits better into lifestyle patterns

Hair research is another area where GHK-CU has gained significant attention