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Homotaurine can cross the blood-brain barrier, exhibits high affinity for GABAA receptors, and has a longer plasma half-life compared to GABA

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Additionally, another study showed participants who received a 15mg weekly dosage for 72 weeks experienced an average weight reduction of 22.5% of their starting body weight

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These concerns motivated the researchers of the current study to explore the risk of excessive weight gain and adverse pregnancy outcomes among women previously ordered GLP-1RAs who discontinued their use during the pre-conceptional period or early pregnancy as compared to unexposed mothers