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Methylation Inhibition Accumulated SAH can inhibit methyltransferases involved in cellular regulation, membrane metabolism and selected detoxification pathways

Trauner D (2023) Neuro-cognitive complications of nephropathic cystinosis

Additionally, as a hydrophilic molecule, DFO has a poor cell permeability and tends to remain in extracellular fluid, which may still limit its efficacy (Hanson et al., 2009

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[6] The sulfate transporters gene family has been classified in up to 5 different groups according to their cellular and sub-cellular gene expression, and possible functioning