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Each estimand carries its own placebo comparator 2.3% under the trial product estimand, 3.0% under treatment policy so the placebo arm moves in the opposite direction to the treatment arm between the two analyses
It's kind of like the fasting blood glucose levels versus the HbA1C, which is like a long-term marker of your blood glucose levels
But no amount of evidence could compete with the certainty shed built from Reddit threads and podcasts
If you still have questions about the type of B12 to use, the dosage necessary, when/how you should use it, etc
Instead, they must apply CPT hierarchy rules
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